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Get Latest Price from the seller Contact Seller. About the Company Year of Establishment Legal Status of Firm Individual - Proprietor. No observable toxicity occurred, as assessed by mortality, body weight gain, histopathology of brain, liver, kidneys, and lungs, or clinical signs of aggression, lethargy, breathing difficulties, diarrhea, mobility, or shivering. Recent toxicity studies performed by an independent toxicology laboratory were conducted to evaluate the mutagenicity and genotoxicity potential of UltraFactor XF colostrum ultrafiltrate.
Mutagenicity was assessed by the Bacterial Reverse Mutation assay. Results revealed that the test article has no mutagenic activity at any of the concentrations tested. Genotoxicity was assessed by the Mammalian Chromosome Aberration test. Results demonstrated that the test article, tested up to the maximum recommended concentration, did not induce structural chromosome aberrations in this mammalian system.
The laboratory concluded that UltraFactor XF is considered not clastogenic in this system. Oral toxicity studies performed by the same toxicology laboratory assessed the potential short-term and long-term toxicity of UltraFactor XF in rats.
Results revealed that no mortality occurred at any given dose. Clinical observations showed no adverse effect of the test article on behavior and physical condition of the animals.
No abnormal body weight gain or food consumption was observed. Ophthalmological and hematological evaluations demonstrated no adverse effect by the test article. Similarly, no changes were observed in clinical chemistry, gross pathology, organ weight, or histopathology at any given dose.
An expert panel of toxicologists have evaluated the above-mentioned toxicity data and concluded that UltraFactor XF is generally recognized as safe GRAS. The use of transfer factors is contraindicated in people receiving immunosuppressive therapy, though actual interactions have not been documented.
The use of transfer factors during pregnancy and nursing has not been evaluated. Fundenberg, H. Lawrence, H. Schlesinger, J. Levin, A. Spitler, and H. Fudenberg, H. See, D, S. Mason, and R. Wilson, G. Newell, and N. Radosevich, J. Scott, and G.
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